参考文献/References:
[1] Bray F,Ferlay J,Soerjomataram I,et al. Global cancer statistics 2018:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin,2018,68(6):394-424.
[2]王军,武亚晶. 放射性心脏损伤研究进展——基础篇[J]. 中华放射肿瘤学杂志,2019,28(10):721-727.
[3] Raghunathan D,Khilji MI,Hassan SA,et al. Radiation-induced cardiovascular disease[J]. Curr Atheroscler Rep,2017,19(5):22.
[4] Mulrooney DA,Hyun G,Ness KK,et al. Major cardiac events for adult survivors of childhood cancer diagnosed between 1970 and 1999:report from the childhood cancer survivor study cohort[J]. BMJ,2020,368:l6794.
[5] Darby SC,Ewertz M,McGale P,et al. Risk of ischemic heart disease in women after radiotherapy for breast cancer[J]. N Engl J Med,2013,368(11):987-998.
[6] Donnelln E,Phelan D,Mccarthy CP,et al. Radiation-induced heart disease:a practical guide to diagnosis and management[J]. Cleve Clin J Med,2016,83(12):914-922.
[7] Aleman BM,van den Belt-Dusebout AW,de Bruin ML,et al. Late cardiotoxicity after treatment for Hodgkin lymphoma[J]. Blood,2007,109:1878-1886.
[8] Guldner L,Haddy N,Pein F,et al. Radiation dose and long term risk of cardiac pathology following radiotherapy and anthracyclin for a childhood cancer[J]. Radiother Oncol,2006,81(1):47-56.
[9] van Nimwegen FA,Ntentas G,Darby SC,et al. Risk of heart failure in survivors of Hodgkin lymphoma:effects of cardiac exposure to radiation and anthracyclines [J]. Blood,2017,129(16):2257-2265.
[10] Veinot JP,Edwards WD. Pathology of radiation-induced heart disease:a surgical and autopsy study of 27 cases[J]. Hum Pathol,1996,27(8):766-773.
[11] Morton DL,Glancy DL,Joseph WL,et al. Management of patients with radiation-induced pericarditis with effusion:a note on the development of aortic regurgitation in two of them[J]. Chest,1973,64(3):291-297.
[12]Gujral DM,Lloyd G,Bhattacharyya S. Radiation-induced valvular heart disease[J]. Heart,2016,102(4):269-276.
[13]Cutter DJ,Schaapveld M,Darby SC,et al. Risk of valvular heart disease after treatment for Hodgkin lymphoma[J]. J Natl Cancer Inst,2015,107(4):djv008.
[14] McGale P,Darby SC,Hall P,et al. Incidence of heart disease in 35,000 women treated with radiotherapy for breast cancer in Denmark and Sweden[J]. Radiother Oncol,2011,100(2):167-175.
[15] Galper SL,Yu JB,Mauch PM,et al. Clinically significant cardiac disease in patients with Hodgkin lymphoma treated with mediastinal irradiation[J]. Blood,2011,117(2):412-418.
[16] 王婷,寇锋军. 肺癌放疗对心电图与心肌酶谱影响的研究[J]. 实用癌症杂志,2016,31(11):1890-1892.
[17] 张凯. 肺癌放疗致心电图与心肌酶谱异常的临床观察[J]. 临床医药文献电子杂志,2017,4(82):16098-16100.
[18] 蒋桂芳,魏月,张巍,等. 放疗对肺癌患者心电图和心肌酶谱的影响[J]. 中国肿瘤临床与康复,2018,25(6):695-697.
[19] Gomez DR,Yusuf SW,Munsell MF,et al. Prospective exploratory analysis of cardiac biomarkers and electrocardiogram abnormalities in patients receiving thoracic radiation therapy with high-dose heart exposure[J]. J Thorac Oncol,2014,9(10):1554-1560.
[20] Strender LE,Lindahl J,Larsson LE. Incidence of heart disease and functional significance of changes in the electrocardiogram 10 years after radiotherapy for breast cancer[J]. Cancer,2015,57(5):929-934.
[21] Farhood B,Ashrafizadeh M,Khodamoradi E,et al. Targeting of cellular redox metabolism for mitigation of radiation injury[J]. Life Sci,2020,250:117570.
[22] Wei J,Wang B,Wang H,et al. Radiation-induced normal tissue damage:oxidative stress and epigenetic mechanisms[J]. Oxid Med Cell Longev,2019,2019:3010342.
[23] Livingston K,Schlaak RA,Puckett LL,et al. The role of mitochondrial dysfunction in radiation-induced heart disease:from bench to bedside[J]. Front Cardiovasc Med,2020,7:20.
[24] Fountain MD,Mclellan LA,Smith NL,et al. Isoflavone-mediated radioprotection involves regulation of early endothelial cell death and inflammatory signaling in Radiation-Induced lung injury[J]. Int J Radiat Biol,2020,96(2):245-256.
[25] Haubner F,Ohmann E,Pohl F,et al. Effects of radiation on the expression of adhesion molecules and cytokines in a static model of human dermal microvascular endothelial cells[J]. Clin Hemorheol Microcirc,2013,54(4):371-379.
[26] Zhang J,He X,Bai X,et al. Protective effect of trimetazidine in radiation-induced cardiac fibrosis in mice[J]. J Radiat Res,2020,61(5):657-665.
[27] Yarnold J,Brotons MC. Pathogenetic mechanisms in radiation fibrosis[J]. Radiother Oncol,2010,97(1):149-161.
[28] Seemann I,Gabriels K,Visser NL,et al. Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature[J]. Radiother Oncol,2012,103(2):143-150.
[29] Zhang K,He X,Zhou Y,et al. Atorvastatin ameliorates radiation-induced cardiac fibrosis in rats[J]. Radiat Res,2015,184(6):611-620.
[30] Wennstig AK,Garmo H,Isacsson U,et al. The relationship between radiation doses to coronary arteries and location of coronary stenosis requiring intervention in breast cancer survivors[J]. Radiat Oncol,2019,14(1):40.
[31] Giordano SH,Kuo YF,Freeman JL,et al. Risk of cardiac death after adjuvant radiotherapy for breast cancer[J]. J Natl Cancer Inst,2005,97(6):419-424.
[32] Darby SC,Mcgale P,Taylor CW,et al. Long-term mortality from heart disease and lung cancer after radiotherapy for early breast cancer:prospective cohort study of about 300,000 women in US SEER cancer registries[J]. Lancet Oncol,2005,6(8):557-565.
[33] Darby SC,Ewertz M,McGale P,et al. Risk of ischemic heart disease in women after radiotherapy for breast cancer[J]. N Engl J Med,2013,368(11):987-998.
[34] Corradini S,Ballhausen H,Weingandt H,et al. Left-sided breast cancer and risks of secondary lung cancer and ischemic heart disease[J]. Strahlenther Onkol,2018,194(3):196-205.
[35] Gaasch A,Sch?necker S,Simonetto C,et al. Heart sparing radiotherapy in breast cancer:the importance of baseline cardiac risks[J]. Radiat Oncol,2020,15(1):117.
[36] Carolyn T,Candace C,Duane FK,et al. Estimating the risks of breast cancer radiotherapy:evidence from modern radiation doses to the lungs and heart and from previous randomized trials[J]. J Clinl Oncol,2017,35(15):1641-1649.
[37] Galper SL,Yu JB,Mauch PM,et al. Clinically significant cardiac disease in patients with Hodgkin lymphoma treated with mediastinal irradiation[J]. Blood,2011,117(2):412-418.
[38] Hooning MJ,Aleman BM,Rosmalen AJ,et al. Cause-specific mortality in long-term survivors of breast cancer:a 25-year follow-up study[J]. Int J Radiat Oncol Biol Phys,2006,64(4):1081-1091.
[39] Paszat LF,Mackillop WJ,Groome PA,et al. Mortality from myocardial infarction after adjuvant radiotherapy for breast cancer in the surveillance,epidemiology,and end-results cancer registries[J]. J Clin Oncol,1998,16(8):2625-2631.
[40] Chang JS,Shin J,Park EC,et al. Risk of cardiac disease after adjuvant radiation therapy among breast cancer survivors[J]. Breast,2019,43:48-54.
[41] Verma V,Cushman TR,Tang C,et al. Toxicity of radiation and immunotherapy combinations[J]. Adv Radiat Oncol,2018,3(4):506-511.
[42]艾星浩,蔡勇,褚倩,等. 放疗联合免疫治疗非小细胞肺癌:前沿学术问题专家交流共识[J]. 中国肺癌杂志,2020,23(6):532-540.
[43] Mahdavi H. Radiation oncologists’ perspectives on reducing radiation-induced heart disease in early breast cancer[J]. Curr Probl Cancer,2020,44(2):100509.
[44] Korreman SS,Pedersen AN,Josipovi? M,et al. Cardiac and pulmonary complication probabilities for breast cancer patients after routine end-inspiration gated radiotherapy[J]. Radiother Oncol,2006,80(2):257-262.
[45] Liu LK,Ouyang W,Zhao X,et al. Pathogenesis and prevention of radiation-induced myocardial fibrosis[J]. Asian Pac J Cancer Prev,2017,18(3):583-587.
[46] Zhang K,He X,Zhou Y,et al. Atorvastatin ameliorates radiation-induced cardiac fibrosis in rats[J]. Radiat Res,2015,184(6):611-620.
[47]van der Veen SJ ,Ghobadi G ,de Boer RA ,et al. ACE inhibition attenuates radiation-induced cardiopulmonary damage[J]. Radiother Oncol ,2015,114(1):96-103.
[48] O’Herron T,Lafferty J. Prophylactic use of colchicine in preventing radiation induced coronary artery disease[J]. Med Hypotheses,2018,111:58-60.
[49] Alite F,Balasubramanian N,Adams W,et al. Decreased risk of radiation pneumonitis with coincident concurrent use of angiotensin-converting enzyme inhibitors in patients receiving lung stereotactic body radiation therapy[J]. Am J Clin Oncol,2018,41(6):576-580.
[50] Yang WS,Yang E,Kim MJ,et al. Momordica charantia inhibits inflammatory responses in murine macrophages via suppression of TAK1[J]. Am J Chin Med,2018,46(2):435-452.
[51] Gu J,Liu K,Li H,et al. Astragalus saponin attenuates the expression of fibrosis-related molecules in irradiated cardiac fibroblasts[J]. Acta Biochim Biophys Sinica(Shanghai),2014,46(6):492-501.
[52] 周游,陈绘颖,王江友,等. 曲美他嗪对大鼠放射性心肌损伤后TNF-α表达的影响[J]. 现代生物医学进展,2014,14(10):1821-1824.