[1]赵越 张梅 李伟 应长江 凌宏威 刘馨 张彤 程雪.血糖控制不佳的2型糖尿病患者心血管病风险分析[J].心血管病学进展,2020,(5):551-555.[doi:10.16806/j.cnki.issn.1004-3934.2020.05.026]
ZHAO Yue,ZHANG Mei,LI Wei,et al.Risk Analysis of Cardiovascular Diseases in Patients with Poorly Controlled Diabetes Mellitus[J].Advances in Cardiovascular Diseases,2020,(5):551-555.[doi:10.16806/j.cnki.issn.1004-3934.2020.05.026]
点击复制
血糖控制不佳的2型糖尿病患者心血管病风险分析(
)
《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]
- 卷:
-
- 期数:
-
2020年5期
- 页码:
-
551-555
- 栏目:
-
- 出版日期:
-
2020-05-25
文章信息/Info
- Title:
-
Risk Analysis of Cardiovascular Diseases in Patients with Poorly Controlled Diabetes Mellitus
- 作者:
-
赵越 张梅 李伟 应长江 凌宏威 刘馨 张彤 程雪
-
(徐州医科大学附属医院内分泌科,江苏 徐州 221000)
- Author(s):
-
ZHAO Yue
; ZHANG Mei; LI Wei; YING Changjiang; LING Hongwei; LIU Xin; ZHANG Tong; CHENG Xue
-
(Department of Endocrinology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000,Jiangsu,China)
-
- 关键词:
-
Risk Analysis of Cardiovascular Diseases in Patients with Poorly Controlled Diabetes Mellitus
- Keywords:
-
Diabetes mellitus; Blood glucose; Cardiovascular risk; Cardiovascular risk factors
- DOI:
-
10.16806/j.cnki.issn.1004-3934.2020.05.026
- 摘要:
-
目的
评估比较血糖控制良好和控制不佳的
2型
糖尿病患者未来
10
年心血管病风险及相关危险因素分析。
方法
收集本院内分泌科住院的
2
型糖尿病患者
549
例，
根据其入院次日空腹糖化血红蛋白（
HbA1c
）测定结果，
分为血糖控制不佳组
（HbA1c>7%）408
例和血糖控制良好组
（HbA1c
≤
7.0%）1
41
例，监测两组年龄、性别、
现居地、
吸烟史、饮酒史、个人疾
病史
、
体重指数
、
腰围、
收缩压、舒张压、血糖、总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白和纤维蛋白原等指标，并应用
Framingham 10
年心血管病事件风险评估模型
（
Framingham
R
isk
S
core
，
FRS
）和
China-PAR模型
预测患者未来
10
年的心血管病发病风险。
结果
血糖控制不佳组收缩压、舒张压、空腹血糖、总胆固醇和低密度脂蛋白胆固醇平均值差异有统计学意义（
P
<0.05
）。
Framingham 10
年心血管病事件风险评估模型和
China-PAR模型
结果
提
示：
血糖控制良好的
2型
糖尿病患者大多属于低、中心血管病风险，
血糖
控制不
佳
的
2型糖尿病
患者大多属于心血管病高风险。
结论
血糖控制不佳的糖尿病患者应更加注意心血管病危险因素的监测与控制以降低其心血管病风险。
- Abstract:
-
Objective To evaluate cardiovascular risk and related risk factors between patients with poorly controlled and patients with well-controlled type 2 diabetes mellitus in the next 10 years. Methods Five hundred and forty-nine diabetic patients enrolled in the study. According to levels of fasting hemoglobin A1c (HbA1c) on the second day after admission, they were divided into poorly controlled diabetes group（HbA1c7%）（n=408）and well-controlled diabetes（HbA1c7%）（n=141）group. The following data and parameters were monitored: age, gender, , smoking and alcohol consumption,diseases history,body mass index,waist circumference,systolic blood pressure, diastolic blood pressure,?blood glucose, total cholesterol(TC), triglycerides, low density lipoprotein cholesterol(LDL-C), high density lipoprotein cholesterol (HDL-C), and fibrinogen(P<0.05). Framingham Stroke Profile and China-PAR were used to predict the risk of cardiovascular diseases over the next decade. Results Systolic blood pressure, diastolic blood pressure, fasting glucose, TC, mean LDL-C are statistically significant higher in patients with poorly controlled diabetes. Framingham 10-year cardiovascular event risk assessment model and China-PAR shows that most of patients with poorly controlled T2DM have a high and very high cardiovascular diseases risk. Conclusion Patients with poorly controlled diabetes should pay more attention to monitoring and controlling of cardiovascular risk factors to reduce their cardiovascular risk
更新日期/Last Update:
2020-08-12