[1]梁科研 杨芳 褚静洁.四维超声心动图评价扩张型心肌病右心室整体收缩功能及其临床意义[J].心血管病学进展,2020,(5):547-550.[doi:10.16806/j.cnki.issn.1004-3934.2020.05.025]
　LIANG Keyan,YANG Fang,CHU Jingjie.Four-dimensional Echocardiography for Evaluation of Right Ventricular Systolic Function in Dilated Cardiomyopathy and Its Clinical Significance[J].Advances in Cardiovascular Diseases,2020,(5):547-550.[doi:10.16806/j.cnki.issn.1004-3934.2020.05.025]
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四维超声心动图评价扩张型心肌病右心室整体收缩功能及其临床意义()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年5期
页码:
547-550
栏目:
出版日期:
2020-05-25

文章信息/Info

Title:
Four-dimensional Echocardiography for Evaluation of Right Ventricular Systolic Function in Dilated Cardiomyopathy and Its Clinical Significance
作者:
梁科研 杨芳 褚静洁
(辽宁省鞍山市中心医院,辽宁 鞍山 114001)
Author(s):
LIANG Keyan ; YANG Fang ; CHU Jingjie
(Liaoning Anshan Central Hospital,Anshan 114001, Liaoning,China)?/html>
关键词:
四维超声心动图; 扩张型心肌病; 右心室整体收缩功能; 临床意义
Keywords:
Four-dimensional echocardiography;  Dilated cardiomyopathy ;  Global right ventricular systolic function ;  Clinical significance
DOI:
10.16806/j.cnki.issn.1004-3934.2020.05.025
摘要:
目的 探讨四维超声心动图评价扩张型心肌病（DCM）右心室整体收缩功能的意义。方法 将医院2017年1月—2018年12月（时间段与后不符合？）收治的68例DCM患者纳为研究对象，根据普通二维超声测量结果，将右心室内径扩大者纳为A组（n=33），右心室内径正常者纳为B组（n=35），并将同期行健康体检者纳为对照组（n=40），所有研究对象均行常规超声心动图检查并存储留取四维超声图像备分析，统计三组左心室内径、射血分数及右心室容积、射血分数，以及右心室总体应变参数[总体长轴峰值应变（GPSL）、总体圆周峰值应变（GPSC）、总体面积峰值应变（GPSA）和总体径向峰值应变（GPSR）]，常规药物治疗4周后，比较DCM患者治疗前后右心室相关参数变化，评价四维超声心电图在评价DCM患者右心室收缩功能中的作用。结果 三组左心室舒张期内径、左心室射血分数、右心室容积以及右心室射血分数均存在显著差异（P＜0.05）；三组GPSL、GPSC、GPSA以及GPSR水平差异显著（P＜0.05）；DCM患者治疗后，其三尖瓣峰值反流速度、右心室射血分数、GPSL、GPSC、GPSA和GPSR水平均较治疗前显著上升（P＜0.05）。结论 四维超声心动图能有效提示DCM患者右心室微观变化，且即使是右心室内径正常的DCM患者，也具有右心室收缩功能障碍，应及时治疗以缓解右心室病变。
Abstract:
Objective To explore the significance of four-dimensional echocardiography for the evaluation of right ventricular systolic function in dilated cardiomyopathy(DCM). Methods 68 patients with DCM admitted to the hospital from June 2017 to June 2018 were selected for the study. According to the results of ordinary two-dimensional ultrasound measurement, the patients with right ventricular diameter enlargement were classified as group A(n=33), and the patients with normal right ventricular diameter were included in group B(n=35), and the examiners who underwent healthy physical examination at the same time were set as control group (n=40). All subjects were examined by conventional echocardiography and stored for analysis of four-dimensional ultrasound images. The ventricular diameter, ejection fraction, right ventricular volume, ejection fraction, and right ventricular total strain parameters [global peak longitudinal strain(GPSL), global peak circumferential strain(GPSC), global peak area strain(GPSA), global peak radial strain(GPSR)] were counted in the three groups. The changes of right ventricular related parameters before and after treatment were also compared among DCM patients. And the effects of four-dimensional echocardiography in evaluating right ventricular systolic function in DCM patients were evaluated. Results There were significant differences in the left ventricular diastolic diameter, left ventricular ejection fraction, right ventricular volume and right ventricular ejection fraction among the three groups (P＜0.05). There were significant differences in the levels of GPSL, GPSC, GPSA and GPSR among the three groups (P＜0.05). After treatment in DCM patients, the tricuspid peak reversal flow velocity, right ventricular ejection fraction, GPSL, GPSC, GPSA and GPSR were significantly higher than before treatment (P＜0.05). Conclusion Four-dimensional echocardiography can effectively indicate the microscopic changes of right ventricle in DCM patients, and even DCC patients with normal right ventricular diameter have obstacles in right ventricular systolic function. It is necessary to give timely treatment so as to relieve right ventricular lesions.?/html>

参考文献/References:

[1].Mcnally EM,Mestroni L.Dilated cardiomyopathy:genetic determinants and mechanisms[J].Circ Res,2017,121(7):731-748.
[2].Zairi I,Mzoughi K,Jabeur M,et al.Right ventricular systolic echocardiographic parameters in dilated cardiomyopathy and prognosis[J].La Tunis Med, 2017,95(2):87-91.
[3].Tamborini G,Brusoni D,Torres Molina JE,et al.Feasibility of a new generation three-dimensional echocardiography for right ventricular volumetric and functional measurements[J].Am J Cardiol,2008,102(4):499-505.
[4].中华医学会心血管病学分会.心肌病诊断与治疗建议[J].中华心血管病杂志,2007,35(1):5-16.
[5].Halliday BP,Gulati A,Ali A,et al.Association between mid-wall late gadolinium enhancement and sudden cardiac death in patients with dilated cardiomyopathy and mild and moderate left ventricular systolic dysfunction[J].Circulation,2017,135(22):2106-2115.
[6].Wang M,Chen K,Chen X,et al.Endomyocardial biopsy in differential diagnosis between arrhythmogenic right ventricular cardiomyopathy and dilated cardiomyopathy:an in vitro simulated study[J].Cardiovasc Pathol,2018,34:15-21.
[7].Lee CK,Margossian R,Sleeper LA,et al.Variability of M-mode versus two-dimensional echocardiography measurements in children with dilated cardiomyopathy[J].Pediatr Cardiol,2014,35(4):658-667.
[8].Cao S,Zhou Q,Chen JL,et al.The differences in left atrial function between ischemic and idiopathic dilated cardiomyopathy patients:a two-dimensional speckle tracking imaging study[J].J Clin Ultrasound,2016,44(7):437-445.
[9].Saeed AK,Sadeghian H,Abbasi SH,et al.Right ventricular outflow tract tachycardia detected by transthoracic and 4-dimensional echocardiography[J]. Minerva Cardioangiol,2009,57(3):359-361.
[10].Sahn DJ,Shentu W,Li X,et al.Use of 4-dimensional echocardiography in the measurement of right ventricular ejection fraction and stroke volume:studies in a dynamic in vitro model[J].J Am Coll Cardiol,2012,59(13):e781-e781.(核对该条？)
[11].朱洪基,余建群,彭礼清. 心电门控双源 CTPA 评价急性肺栓塞及其右心室功能[J]. 心血管病学进展,2019,40(6):955-959.
[12].Oon YY,Amin NHM,Said A,et al.Accuracy and reproducibility of real-time three-dimensional echocardiography versus two-dimensional echocardiography in measuring left ventricular volumes and ejection fraction in daily clinical practice[J].Int J Cardiol,2017,249:s18-s19.(核对该条？)
[13].Zhang Z,Zhu M,Ashraf M,et al.Right ventricular strain analysis from three-dimensional echocardiography by using temporally diffeomorphic motion estimation[J].Med Phys,2014,41(12):122902.
[14].Watanabe K,Hashimoto I,Ibuki K,et al.Evaluation of right ventricular function using single-beat three-dimensional echocardiography in neonate [J].Pediatr Cardiol,2015,36(5):918-924.

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备注/Memo

备注/Memo:
基金项目：辽宁省教育厅科学研究一般项目（L2013698）
更新日期/Last Update: 2020-08-12