[1]郭岐龙 芦颜美 张玲 张疆华 邢强 祖克拉·吐尔洪 李耀东 周贤惠 汤宝鹏.新疆地区老年慢性心力衰竭住院患者的病因、合并症及药物治疗的多中心回顾性分析[J].心血管病学进展,2020,(4):414-418.[doi:10.16806/j.cnki.issn.1004-3934.2020.04.021]
　GUO Qilong,LU Yanmei,ZHANG Ling,et al.Etiology, Comorbidity and Drug Treatment of Elderly Inpatients with Chronic Heart Failure in Xinjiang: A Multi-center Retrospective Study[J].Advances in Cardiovascular Diseases,2020,(4):414-418.[doi:10.16806/j.cnki.issn.1004-3934.2020.04.021]
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新疆地区老年慢性心力衰竭住院患者的病因、合并症及药物治疗的多中心回顾性分析()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年4期
页码:
414-418
栏目:
论著
出版日期:
2020-04-25

文章信息/Info

Title:
Etiology, Comorbidity and Drug Treatment of Elderly Inpatients with Chronic Heart Failure in Xinjiang: A Multi-center Retrospective Study
作者:
郭岐龙 芦颜美 张玲 张疆华 邢强 祖克拉·吐尔洪 李耀东 周贤惠 汤宝鹏
(新疆医科大学第一附属医院心脏中心,新疆 乌鲁木齐 830054)
Author(s):
GUO Qilong;  LU Yanmei;  ZHANG Ling;  ZHANG Jianghua;  XING Qiang;  Zukela·Tuerhong;  LI  Yaodong;  ZHOU Xianhui;  TANG Baopeng
(Heart Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054 , Xinjiang, China)
关键词:
慢性心力衰竭; 老年患者; 合并症; 药物治疗
Keywords:
Chronic heart failure;  Elderly patients;  Comorbidity;  Drug treatment
DOI:
10.16806/j.cnki.issn.1004-3934.2020.04.021
摘要:
目的 调查新疆地区老年慢性心力衰竭（心衰）住院患者的常见病因、合并症特点及药物治疗情况，为新疆地区老年慢性心衰患者规范化防治提供科学依据。方法 采用多中心回顾性横断面调查研究方法，选择2018年1月——10月新疆地区13家医院共1 493例慢性心衰住院患者纳入本研究。根据患者年龄，分为普通老年组、老老年组，比较两组心衰患者的临床特点、病因、非心血管系统合并症、改善心衰预后的药物使用情况。结果 普通老年组和老老年组性别、心功能分级差异无统计学意义（ P＞0.05）。老老年组射血分数保留性心衰比例高于普通老年组、射血分数降低性心衰比例低于普通老年组，差异有统计学意义（P＜0.05）。高血压、冠心病是两组最常见的心衰病因，老老年组平均病因数量、非心血管系统合并症数量均高于普通老年组[（1.95±0.71）vs（1.70±0.58）、（1.89±0.89）vs（1.55±0.71），P均＜0.05]。老老年组心房颤动、心脏瓣膜病、脑血管疾病、外周血管病、肾功能不全、慢性贫血比例高于普通老年组，而冠心病、糖尿病比例低于普通老年组，差异均有统计学意义（P＜0.05）。老老年组出院带药中血管紧张素转换酶抑制剂/血管紧张素Ⅱ受体拮抗剂/血管紧张素受体脑啡肽酶抑制剂、β受体阻滞剂、醛固酮拮抗剂使用率均低于普通老年组[（65.9% vs 76.7%、51.0% vs 70.8%、62.7% vs 69.4%，P均＜0.05）。结论 新疆地区老年慢性心衰患者存在多心血管病因、合并多种疾病的特点，老老年患者合并症更多、抗心衰药物应用比例较低。
Abstract:
Objective To investigate the characteristics of etiology, non-cardiovascular comorbidity and drug treatment of elderly patients with chronic heart failure (CHF) in Xinjiang, and to provide scientific evidence for prevention and treatment of elderly patients with CHF. Methods This is a multicenter retrospective cross-sectional study. a total of 1 493 inpatients with CHF from 13 hospitals in Xinjiang from January to October 2018 were investigated. Participants were classified into the general elderly group and the old elderly group according to the age of the patients. The clinical characteristics, etiology, non-cardiovascular system comorbidity and drug use to improve the prognosis of heart failure were compared between the two groups. Results There was no significant difference in gender and cardiac function between two groups ( P>0.05). The proportion of HFpEF in the old elderly group was higher than that in the general elderly group, and the proportion of HFrEF was lower (P<0.05). Hypertension and coronary heart disease are the most common causes of CHF in both groups. The average number of cardiovascular etiologic factors and non-cardiovascular comorbidities in the old elderly group was higher than that in the general elderly group [(1.95±0.71) vs (1.70±0.58) and (1.89±0.89) vs (1.55±0.71), P < 0.05 ]. The proportion of old elderly patients with atrial fibrillation, chronic heart valvular disease, cerebrovascular disease, peripheral vascular disease, renal insufficiency and anemia was higher than that of the general elderly group, while the proportion with coronary heart disease and diabetes was lower (P<0.05). The usage rates of ACEI/ARB/ARNI, beta-blocker and aldosterone antagonist in the old elderly group were lower than those in the general elderly group (65.9% vs 76.7%, 51.0% vs 70.8% and 62.7% vs 69.4%, P<0.05). Conclusion The elderly patients with CHF in Xinjiang have the characteristics of multiple causes and co-morbidity. Old elderly patients have more complications and lower proportion of anti-heart failure drugs use.

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备注/Memo

备注/Memo:
基金项目：国家重点研发计划（2016YFC0900905）
通讯作者：汤宝鹏，E-mail: tangbaopeng1111@163.com

收稿日期：2019-10-22 

更新日期/Last Update: 2020-07-29