[1]曹月诚 羡海英 石秋林 王金星 王小祥 陈登峰.卵圆孔未闭封堵术在少量右向左分流患者中的临床疗效评价[J].心血管病学进展,2019,(7):1062-1066.[doi:10.16806/j.cnki.issn.1004-3934.2019.07.024]
 CAO Yuecheng,XIAN Haiying,SHI Qiulin,et al.Clinical Evaluation of Patent Foramen Ovale Closure in Slight Right-to-left Shunt atients[J].Advances in Cardiovascular Diseases,2019,(7):1062-1066.[doi:10.16806/j.cnki.issn.1004-3934.2019.07.024]
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卵圆孔未闭封堵术在少量右向左分流患者中的临床疗效评价()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2019年7期
页码:
1062-1066
栏目:
论著
出版日期:
2019-10-25

文章信息/Info

Title:
Clinical Evaluation of Patent Foramen Ovale Closure in Slight Right-to-left Shunt atients
作者:
曹月诚 羡海英 石秋林 王金星 王小祥 陈登峰
(衡水市人民医院心外科,河北 衡水 053000)
Author(s):
CAO Yuecheng XIAN Haiying SHI Qiulin WANG Jinxing WANG XiaoxiangCHEN Dengfeng
(Department of Cardial Surgery, People’s Hospital of Hengshui City, Hengshui 053000, China.)
关键词:
卵圆孔未闭右向左分流经导管封堵术卒中
Keywords:
Patent foramen ovale Right-to-left shunt Transcatheter closure
DOI:
10.16806/j.cnki.issn.1004-3934.2019.07.024
摘要:
目的 探讨伴有少量右向左分流(RLS)的卵圆孔未闭(PFO)行经导管封堵术的临床疗效、安全性及预后。方法 本研究选取20157月—2017年12月衡水市人民医院心外科行PFO封堵术的患者共30例,其中伴有少量RLS者11例(A1组)伴有中-大量RLS者19例(A2组);选取同期行药物治疗的PFO患者30例为对照组(B组)。对比分析了各组卒中复发率手术组的手术成功率及预后等指标。结果 经导管封堵少量RLS组与中-大量RLS组术后均无残余分流,手术成功率84.6%,与药物治疗相比,少量RLS组行PFO封堵术可取得与伴有中-大量RLS组同样的临床疗效,均可降低卒中复发率。结论 伴有少量RLS的PFO患者亦考虑行PFO封堵术
Abstract:
Objective To investigate the clinical efficacy, safety and prognosis of transcatheter patent foramen ovale (PFO) closure for a slight right-to-left shunt (RLS). Methods A total of 30 patients who underwent PFO occlusion from July 2015 to December 2017 in Hengshui people’s Hospital were selected, including 11 patients with a small amount of RLS (A1 group) and 19 patients with moderate to large RLS (A2 group). 30 patients with PFO who were treated with drugs at the same time were selected as control group (group B). The recurrence rate of stroke, the success rate of operation and prognosis in each group were compared and analyzed. Results There was no residual shunt in transcatheter closure of small amount of RLS group and medium and large amount of RLS group, and the success rate of operation was 84.6%. Compared with drug therapy, PFO occlusion in a small amount of RLS group could achieve the same clinical effect as that of medium and large amount of RLS group, and significantly reduce the recurrence rate of stroke. Conclusion PFO occlusion should also be considered for PFO patients with a small amount of RLS. However, further prospective studies are needed

参考文献/References:

[1].Hoffman JIE, Kaplan S. The incidence of congenital heart disease[J]. J Am Coll Cardiol, 2002, 39(12): 1890-1900.
[2].[2]黄浩佳,胡海波. 经导管卵圆孔未闭封堵术后残余分流影响因素及研究现状分析[J].心血管病学进展,2017,38(3):243-246.
[3].[3]中华医学会心血管内科分会, 中国医师协会心血管内科分会. 卵圆孔未闭预防性封堵术中国专家共识[J]. 中国循环杂志2017,32(3):209-2014.
[4].[4] 赵龙, 郭俊晓, 王坚, . 卵圆孔未闭经导管封堵术22例临床分析[J]. 中国药物与临床, 2017(1):91-92.
[5].[5] 张云, 曾智. 卵圆孔未闭封堵治疗预防脑卒中的再认识[J]. 心血管病学进展, 2014, 35(3):275-278.
[6].[6] Carroll JD, Saver JL, Thaler DE, et al. Closure of patent foramen ovale versus medical therapy after cryptogenic stroke [J]. N Engl J Med, 2013, 368(12):1092-1100.
[7].[7] Diener HC , Gerloff C , Thaler DE, et al. Closure of Patent Foramen Ovale and Cryptogenic Stroke: Unresolved Issues[J]. Current Neurology and Neuroscience Reports, 2018, 18(12): :92.
[8].[8]Pristipino C, Anzola GP, Ballerini L, et al. Management of patients with patent foramen ovale and cryptogenic stroke:a collaborative, mutidisciplinary, position paper: executive summary [J]. Catheter Cardiovasc Interv, 2013, 82(1):122-129.
[9].[9]Farb A, Ibrahim N G, Zuckerman BD. Patent Foramen Ovale after Cryptogenic Stroke-Assessing the Evidence for Closure[J]. New England Journal of Medicine, 2017, 377(11):1006-1009.
[10].[10] Meier B, Kalesan B, Mattle HP, et al. Percutaneous closure of patent foramen ovale in cryptogenic embolism[J]. N Engl J Med, 2013, 368(12):1083-1091.
[11].[11]Brogno D,Lancaster G,Rosenbaum M. Embolus interuptusN Engl J Med,1994330(5): 1761-1762.

备注/Memo

备注/Memo:
(基金项目:衡水市科技计划项目(2016014086Z)收稿日期:2019-06-27
更新日期/Last Update: 2019-12-17