[1]王其海,综述.抗凝药比伐卢定临床应用进展[J].心血管病学进展,2016,(2):208-212.[doi:10.16806/j.cnki.issn.1004-3934.2016.02.029]
 WANG Qihai.Advance in Research on Clinical Application of Anticoagulant Drug Bivalirudin[J].Advances in Cardiovascular Diseases,2016,(2):208-212.[doi:10.16806/j.cnki.issn.1004-3934.2016.02.029]
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抗凝药比伐卢定临床应用进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2016年2期
页码:
208-212
栏目:
综述
出版日期:
2016-04-20

文章信息/Info

Title:
Advance in Research on Clinical Application of Anticoagulant Drug Bivalirudin
作者:
王其海综述
皖北煤电集团总医院心血管内科,安徽 宿州 234000
Author(s):
WANG Qihai
Department of Cardiology,General Hospital of Wanbei Coal Group, Suzhou 234000, Anhui, China
关键词:
比伐卢定 抗凝药 直接凝血酶抑制剂 临床应用
Keywords:
Bivalirudin Anticoagulants Direct inhibitor of thrombin Clinical application
分类号:
R541
DOI:
10.16806/j.cnki.issn.1004-3934.2016.02.029
文献标志码:
A
摘要:
比伐卢定是一种新型直接凝血酶抑制剂,2000年被美国食品药品监督管理局批准应用于临床。比伐卢定由水蛙素提炼而出,利用其有效控制凝血酶正常机能的特性发挥作用,国际上通过让其他抗凝药物和它做对比实验,发现其能够取代一般肝素以及血小板糖蛋白Ⅱb/Ⅲa受体阻滞剂治疗药物用于手术过程中的抗凝治疗所起到的效果。现具体介绍该药物对应的药效和它在治疗心血管疾病的临床表现。
Abstract:
Bivalirdin is a direct thrombin inhibitor approved by US Food and Drug Administration in 2000.It is an analogue of hirudin that can inhibit the active site of thrombus.International studies have compared it with other anticoagulants and shown that bivalirudin can substitute for heparin or glycoprotein Ⅱb/Ⅲa inhibitors in patients undergoing invasive treatment.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介:王其海(1972—),主治医师,硕士,主要从事心血管病介入治疗研究。Email:894273282@qq.com
更新日期/Last Update: 2016-03-25