[1]王晶于,综述,李骊华,等.阻塞性睡眠呼吸暂停低通气综合征与难治性高血压[J].心血管病学进展,2016,(2):117-120.[doi:10.16806/j.cnki.issn.1004-3934.2016.02.005]
　WANG Jingyu,LI Lihua.Obstructive Sleep Apnea Hypopnea Syndrome and Resistant Hypertension[J].Advances in Cardiovascular Diseases,2016,(2):117-120.[doi:10.16806/j.cnki.issn.1004-3934.2016.02.005]
点击复制

阻塞性睡眠呼吸暂停低通气综合征与难治性高血压()
分享到：

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2016年2期
页码:
117-120
栏目:
综述
出版日期:
2016-04-20

文章信息/Info

Title:
Obstructive Sleep Apnea Hypopnea Syndrome and Resistant Hypertension
作者:
王晶于; 综述; 李骊华; 审校
重庆医科大学附属第一医院心血管内科,重庆 400016
Author(s):
WANG Jingyu; LI Lihua
WANG Jingyu,LI Lihua
关键词:
阻塞性睡眠呼吸暂停低通气综合征;  难治性高血压;  持续气道正压通气
Keywords:
Obstructive sleep apnea hypopnea syndrome;  Resistant hypertension;  Continuous positive airway pressure
分类号:
R544.1
DOI:
10.16806/j.cnki.issn.1004-3934.2016.02.005
文献标志码:
A
摘要:
阻塞性睡眠呼吸暂停低通气综合征不仅是高血压的独立危险因素,还是难治性高血压的重要病因之一。改善患者睡眠呼吸暂停低通气情况可为难治性高血压的治疗提供方法。现对阻塞性睡眠呼吸暂停低通气综合征作用于难治性高血压的相关机制及治疗方法做一综述。
Abstract:
Obstructive sleep apnea hypopnea syndrome is an independent risk factor of hypertension, as well as one of the important causes for resistant hypertension.Improved sleep apnea hypopnea condition may provide a method for the treatment of resistant hypertension.This article reviews the role of obstructive sleep apnea hypopnea syndrome in the mechanism of resistant hypertension as well as the treatment of resistant hypertension associated with obstructive sleep apnea hypopnea syndrome.

参考文献/References:

[1] Luyster FS, Kip KE, Buysse DJ,et al.Traditional and nontraditional cardiovascular risk factors in comorbid insomnia and sleep apnea[J].Sleep,2014,37(3):593-600.
[2] Daugherty SL,Powers JD,Magid DJ,et al.Incidence and prognosis of resistant hypertension in hypertensive patients[J].Circulation,2012,125(13):1635-1642.
[3] Li J, Chen X, Sun J.Is the grading system of the severity of the OSAHS used presently rational or not?: from the view of incidence of hypertension in different severity groups[J].Eur Arch Otorhinolaryngol, 2014, 271(9):2561-2564.
[4] Pham LV,Schwartz AR.The pathogenesis of obstructive sleep apnea[J].J Thorac Dis,2015,7(8):1358-1372.
[5] Ma W,Zhang Y.Low rate of resistant hypertension in Chinese patients with hypertension:an analysis of the HOT-CHINA study[J].J Hyertens,2013,31(12):2386-2390.
[6] Dudenbostel T, Calhoun DA.Resistant hypertension, obstructive sleep apnoea and aldosterone[J].J Hum Hypertens,2012,26(5):281-287.
[7] 李南方,韩瑞梅,严治涛,等.高血压合并阻塞性睡眠呼吸暂停低通气综合征患者心血管危险因素分析[J].中华高血压杂志,2011,4(19):361-364.
[8] Schmieder RE,Redon J,Grassi G,et al.ESH position paper,renal denervation—all interventional therapy of resistant hypertension[J].J Hypertens,2012,30(5):837-841.
[9] Pathak A,Girerd X,Azizi M,et al.Expert consensus:renal denervation for the treatment of hypertension[J].Diagn Interv Imagin,2012,93(5):386-389.
[10] Han RM, Li NF, Yan ZT, et al.Analysis of influencing factors on circadian blood pressure of hypertensive patients with obstructive sleep apnea-hypopnea syndrome[J].Zhonghua Xin Xue Guan Bing Za Zhi,2013,41(9):751-755.
[11] Kanika B, James AS,Yan NS,et al.Circadian variability of fibrinolytic markers and endothelial function in patients with obstructive sleep apnea[J].Sleep,2014,37(2):359-367.
[12] Khaled AK,Sheena D,Nirav S,et al.Resistant hypertension and obstructive sleep apnea in the setting of kidney disease[J].J Hypertens,2012,30(5):960-966.
[13] Wang Z, Liang YS.Obstructive sleep apnea syndrome(OSAS)and hypertension:pathogenic mechanisms and possible therapeutic approaches[J].Ups J Med Sci,2012,117(4):370-382.
[14] Elzbieta K,Jessie PB,Douglas NC,et al.Molecular biomarkers of vascular dysfunction in obstructive sleep apnea[J].PLoS One,2013,8(7):e70559.
[15] Belaidi E, Joyeux FM, Ribuot C,et al.Major role for hypoxia inducible factor-1 and the endothelin system in promoting myocardial infarction and hypertension in an animal model of obstructive sleep apnea[J].J Am Coll Cardiol,2009,53(15):1309-1317.
[16] Maria DB,Mario F,Lorenzo L,et al.Oxidative stress mediated arterial dysfunction in patients with obstructive sleep apnoea and the effect of continuous positive airway pressure treatment[J].BMC Pulm Med,2012,12:36.
[17] Bekci TT,Kayrak M, Kiyici A,et al.The association among lipoprotein-associated phospholipase A2 levels, total antioxidant capacity and arousal in male patients with OSA[J].Int J Med Sci,2011,8(5):369-376.
[18] Carpagnano GE, Spanevello A, Sabato R, et al.Systemic and airway inflammation in sleep apnea and obesity: the role of ICAM-1 and IL-8[J].Transl Res,2010,155(1):35-43.
[19] Cofta S, Wysocka E, Dziegielewska-Gesiak S, et al.Plasma selectins in patients with obstructive sleep apnea[J].Adv Exp Med Biol,2013,756:113-119.
[20] 吕荣,吴巧珍,严炜,等.顽固性高血压合并阻塞性睡眠呼吸暂停综合征的临床特点[J].中国循证心血管医学杂志,2013,2(5):62-63.
[21] 黄蓉,肖毅,钟旭,等.阻塞性睡眠呼吸暂停低通气综合征与高血压及瘦素的关系[J].中国医学科学院学报,2010,32(2):157-161.
[22] Vatansever E, Surmen-Gur E, Ursavas A,et al.Obstructive sleep apnea causes oxidative damage to plasma lipids and proteins and decreases adiponectin levels[J].Sleep Breath,2011,15(3):275-282.
[23] Nakagawa Y, Kishida K, Kihara S, et al.Nocturnal falls of adiponectin levels in sleep apnea with abdominal obesity and impact of hypoxia-induced dysregulated adiponectin production in obese murine mesenteric adipose tissue[J].J Atheroscler Thromb,2011,18(3):240-247.
[24] Jamaluddin MS, Weakley SM, Yao Q, et al.Resistin:functional roles and therapeutic considerations for cardiovascular disease[J].Br J Pharmacol,2012,165(3):622-632.
[25] Bonsignore MR, Esquinas C, Barcelo A, et al.Metabolic syndrome, insulin resistance and sleepiness in real-life obstructive sleep apnoea[J].Eur Respir J, 2012,39(5):1136-1143.
[26] Sushmita P, Kristen W, Josiane B, et al.Obstructive sleep apnea in young lean men:impact on insulin sensitivity and secretion[J].Diabetes Care,2012,35(11):2384-2389.
[27] 李静静,张罗献,马利军.阻塞性睡眠呼吸暂停低通气综合征合并高血压的临床研究[J].中国综合临床,2013,29(1):7-10.
[28] Nural S,Gunay E,Halici B,et al.Inflammatory processes and effects of continuous positive airway pressure(CPAP)in overlap syndrome[J].Inflammation,2013,36(1):66-74.
[29] Lucas MD, Schafer B, Atul M, et al.New developments in the use of positive airway pressure for obstructive sleep apnea[J].J Thorac Dis,2015,7(8):1323-1342.
[30] 刘建捷,卢宏志,于静,等.口腔矫治器治疗阻塞性睡眠呼吸暂停综合征合并高血压的原因探讨[J].陕西医药杂志,2014,(4):731-733.
[31] Witkowski A, Prejbisz A, Florczak E, et al.Effects of renal sympathetic denervation on blood pressure, sleep apnea course, and sleep apnea[J].Hypertension,2011,58(4):559-565.
[32] 江小运,王钧,靳文,等.中等强度有氧运动对难治性高血压合并阻塞性睡眠呼吸暂停综合征患者的影响[J].岭南急诊医学杂志,2014,(2):100-102.

相似文献/References:

[1]段兴连,综述,常静,等.阻塞性睡眠呼吸暂停低通气综合征及其干预治疗对心血管疾病的临床意义[J].心血管病学进展,2016,(3):289.[doi:10.16806/j.cnki.issn.1004-3934.2016.03.019]
　DUAN Xinglian,CHANG Jing.Clinical Significance of OSAHS and Its Intervention Therapy on Cardiovascular Disease[J].Advances in Cardiovascular Diseases,2016,(2):289.[doi:10.16806/j.cnki.issn.1004-3934.2016.03.019]
[2]梁二鹏,综述,张慧敏,等.难治性高血压中睡眠呼吸暂停低通气综合征与血浆醛固酮水平的相关性[J].心血管病学进展,2016,(4):358.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.008]
　LIANG Erpeng,ZHANG Huimin.The Relationship Between Plasma Aldosterone Concentration and Sleep Apnea Hypopnea Syndrome in Resistant Hypertension[J].Advances in Cardiovascular Diseases,2016,(2):358.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.008]
[3]杨占奇 王宏宇.睡眠障碍与血管功能的关系研究进展[J].心血管病学进展,2022,(5):428.[doi:10.16806/j.cnki.issn.1004-3934.2022.05.011]
　YANG Zhanqi,WANG Hongyu,,et al.The Relationship Between Sleep Disorder and Vascular Function[J].Advances in Cardiovascular Diseases,2022,(2):428.[doi:10.16806/j.cnki.issn.1004-3934.2022.05.011]

备注/Memo

备注/Memo:
作者简介:王晶于(1991—)在读硕士,主要从事高血压研究。Email:1367426925@qq.com 通信作者:李骊华(1970—)副主任医师,博士,主要从事高血压与动脉粥样硬化研究。Email:lilihua926@163.com
更新日期/Last Update: 2016-03-25