[1]龚剑萍,刘剑.C-Kit+心脏干细胞在心肌修复中的作用[J].心血管病学进展,2016,(1):62-65.[doi:10.16806/j.cnki.issn.1004-3934.2016.01.016]
　GONG Jianping,LIU Jian.6Action of C-Kit+ Cardiac Stem Cells in Myocardial Repairment[J].Advances in Cardiovascular Diseases,2016,(1):62-65.[doi:10.16806/j.cnki.issn.1004-3934.2016.01.016]
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C-Kit+心脏干细胞在心肌修复中的作用()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2016年1期
页码:
62-65
栏目:
综述
出版日期:
2016-02-20

文章信息/Info

Title:
6Action of C-Kit+ Cardiac Stem Cells in Myocardial Repairment
作者:
龚剑萍; 刘剑
重庆医科大学附属第一医院心血管内科,重庆 400016
Author(s):
GONG Jianping; LIU Jian
Department of Cardiology,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China
关键词:
C-Kit受体;  心脏干细胞;  心肌修复
Keywords:
C-Kit receptor;  Cardiac stem cells;  Myocardial repairment
分类号:
R542.2
DOI:
10.16806/j.cnki.issn.1004-3934.2016.01.016
文献标志码:
A
摘要:
终末期冠心病是因大量心肌细胞丧失功能而致不可逆转性损害,以心力衰竭为主要表现的临床综合征。自发现C-Kit+心脏干细胞可分化为心肌细胞后,移植C-Kit+心脏干细胞促进心肌的修复便成为基础和临床研究的热点之一。尽管还有诸多问题尚待解决,但这为终末期心肌修复的研究带来新的方向。现就C-Kit受体及配体、C-Kit+心脏干细胞及其在心肌修复中的作用、局限性做一综述。
Abstract:
End-stage coronary heart disease is caused by the loss of function of myocardial cells in large quantities resulting in direct irreversible damage and manifested into heart failure. As C-Kit+ cardiac stem cells(C-Kit+ CSCs)have been reported to differentiate into myocardial cells,the basic and clinical research has focused on transplanting C-Kit+ CSCs to the myocardial lesions to promote the repair of myocardial cell. Although many problems remain unsolved, this focus has developed a new direction in the research of cardiac treatment. In this paper, we reviewed the C-Kit receptor and its ligand, C-Kit+ CSCs and their actions in myocardial repair as well as relevant limitations.

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备注/Memo

备注/Memo:
作者简介:龚剑萍(1991—),硕士,主要从事心肌再生方面研究。Email:490213514@qq.com
通信作者:刘剑(1966—),副主任医师,主要从事动脉粥样硬化方面研究。Email:liujian819@126.com
更新日期/Last Update: 2016-02-20